Paragon Biosciences is a life-science company located in Chicago, IL. Jeff Aronin has been the chairman and CEO of Paragon Biosciences since 2010. Aronin co-founded Ovation Pharmaceuticals in 2000. After selling the company in 2009 for $900 million, Lundbeck asked Jeff to continue serving in his position as chairman during the transition.
Before he founded Paragon, Jeff met with a physician who had a dilemma about how to treat a child who dealt with seizures. He had two choices. He had to decide whether to perform the surgical procedure or treat the patient with medicine. That doctor chose to use medicine. The symptoms drastically improved and the child did not have to endure surgery. When he witnessed that event, it convinced Mr. Aronin a “medication first” treatment approach could be the answer for many ailments, where people suffered without hope.
Paragon collaborates with health providers and gathers data about illnesses that do not typically receive research attention or funding. Paragon focuses on identifying the diseases that lack treatment options. Their research team investigates the source of the ailment then uses the data to help them discover which therapy hasn’t been attempted. This helps them generate alternatives that could lead to better results. Over the past 10 years, 13 of the medications they manufactured have been approved by the FDA. Although they are pleased with the results, they are not satisfied by them. The Paragon family companies Jeff Aronin co-founded are Castle Creek Pharmaceuticals and Harmony Biosciences. Harmony leads research that is seeking breakthroughs for narcolepsy and cataplexy because they focus on disorders of the central nervous system. Castle Creek concentrates on rare genetic dermatological disorders like epidermolysis bullosa simplex.
In addition to Paragon’s impact in medical research and collaborations with physicians, Jeff personally donates to various organizations committed to patient improvement such as Diabetes Research Foundation and Pharmacological Treatment of Epilepsy, among others. Jeff also supports multiple agencies that are dedicated to change through education both locally and globally. Charities included on this list are Teaching Tolerance, U.S. Holocaust Museum, Boys and Girls Club of Chicago and many more.